However, with the litany of available options, making the proper prescription decisions has only become more challenging, especially as the one-size-fits-all approach to writing scripts has been deemed ineffective in properly addressing patient needs. At Captiva Lab, we are dedicated to helping medical care providers make the best possible choices. With pharmacogenomics testing, we can help you design a custom treatment plan ideal for your patients.
What is Pharmacogenomics?
Pharmacogenomics refers to the practice of testing biological information to determine the right medication and right dosage for your patients. Also known as genetic pharmacology, gene site testing, PGx, or pharmacogenetics, we are able to help you understand how and why medications will affect your patients, ensuring you make an educated decision in the course of providing care.
The idea that medications do not affect all patients equally is not new, but historically, choosing the right medication resulted in a trial and error approach to medicine. With PGx, it’s now possible to identify the genetic factors that may impact how and why particular medications work – and why they don’t. Rather than cycling through several similar medications until you find one that appeals to a patient, we can help you approach care from an educated perspective.
Our services are designed to fully support your role as a care provider, offering testing panels that cover numerous classes of drugs and relevant biomarkers. With our help, you can ensure your patients receive prescriptions tailored to their unique physiology.
How Pharmacogenomic Testing Works
Pharmacogenomic testing targets particular biomarkers that pertain to a specific class of medication. In doing so, it is possible to determine areas in which drugs are most likely to be effective.
When medications are consumed, their components are metabolized by enzymes throughout the body that are regulated by metabolic pathways. In theory, these pathways would function in the same way in all humans, but genetic differences can create subtle changes that alter how these pathways work. For this reason, a medication that works for one person may have radically different effects on another. Our PGx testing highlights these difference, helping to hone in on what will work best, why it will work, and in what doses.
Please note that genetic pharmacology does not screen for medication conditions; it simply tests for genetic markers that may impact how medications respond within a patient’s body.
The Importance of Pharmacogenomics
Medicine is a science, but the differences in the human genome often make providing care part medical knowledge and part best guesswork. Pharmacogenomics can bridge this gap, helping doctors to better take a scientific approach to medication prescription and management. Without it, it’s possible to spend months or even years cycling through medications, looking for the right fit. This can be stressful, uncomfortable, and even potentially dangerous for patients.
Genetic components can account for anywhere between 20% and 95% of patient variability. In spite of this, roughly 4 billion prescriptions are filled in the U.S. each year, and almost none take into account patient genetic makeup to avoid adverse drug reactions. Further, 3% to 7% of hospital admissions are caused by these kinds of reactions, indicating a serious issue in need of attention. Pharmacogenomics can be extremely effective in addressing these shortcomings, providing a solid starting place for prescription regimens.
Pharmacogenomics can offer countless benefits to your practice and your patients, including: